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The high prevalence of clinical inertia (approximately 69% to 70% at both visits) highlights a pervasive issue of under-treatment in this patient population, which likely contributes to poor asthma control and increased morbidity.
The failure to initiate or escalate ICS therapy according to GINA 2021 guidelines reveals gaps in physician adherence to evidence-based treatment protocols, which is critical for preventing asthma exacerbations and progression.
The association of allergic-related comorbidities with increased clinical inertia suggests that complexity in patient presentations complicates treatment decisions, potentially leading to suboptimal care.
Longer asthma duration (5–10 years) markedly increases the risk of clinical inertia, indicating that patients with established disease may face barriers to treatment modification or escalation, possibly due to patient preferences or provider perceptions.
Severity of asthma is a strong predictor of clinical inertia, with moderate and severe persistent asthma cases far more likely to experience under-treatment, emphasizing the need for proactive management in patients with more serious disease presentations.
The study’s prospective design adds reliability to the assessment of clinical inertia over time in this specific healthcare setting, and its findings call attention to the need for targeted interventions to improve guideline adherence and patient outcomes in low-resource environments.
The observed poor knowledge and suboptimal adherence rates among patients further complicate effective asthma management, pointing to the necessity of patient education alongside provider-focused strategies.
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